Preservation of cardiac function by coronary thrombolysis during acute myocardial infarction: Fact or myth?

Acute myocardial infarction: thrombolysis.

nfarction is the most intensively studied medical intervention in the history of clinical investigation, with more than 200 000 patients enrolled in large scale, worldwide trials. The results of these trials have led to an irrevocably altered approach, with routine use of reperfusion treatment. Streptokinase, tissue plasminogen activator (t-PA), and new plas-minogen activators have been shown t...

Coronary spasm in myocardial infarction: fact or fiction?

Prehospital coronary thrombolysis. A new strategy in acute myocardial infarction.

Thirty-four patients with acute myocardial infarction were treated prospectively using a new strategy of prehospital intravenous streptokinase given by a physician-operated mobile intensive care unit. The 29 prehospital-treated patients who had experienced no previous myocardial infarction were compared to a similar group treated with streptokinase inhospital. Patients receiving streptokinase i...

[Thrombolysis in acute myocardial infarction].

This is an extensive review of thrombolysis in myocardial infarction with discussions of the pathophysiology of occlusion, clinical occlusion and rationale for thrombolysis, thrombolytic agents, results of thrombolysis (incidence of reperfusion, left ventricular function, and mortality), complications of thrombolytic therapy, reocclusion, and current recommendations.

Thrombolysis for Acute Myocardial Infarction

Indlvldual studies of patency rates and left ventricular (LV) function after thrombolysis have generally been limited by small numbers of observations, wide confidence intervals, and limRed numbers of time points. To obtain a more reliable estimate of patterns of patency and LV ejection fraction, a systematic overview of anglographic studies was performed after itira= venous thrombolytic therap...